The Crumpler Karachi Outpost Camera Backpack ($265) can handle anything you throw at it. It has a large interior to house your custom DSLR gear, lenses, and accessories. The 31-liter compartment features a customizable floating floor with twelve velcro mounted dividers plus a laptop sleeve that’s big enough to hold an 11-inch MacBook. A front cargo compartment is perfect for your smaller items like memory cards, batteries, and filters. And to keep you gear dry it comes with an elastic rain cover made from a water resistant 600D field twill.